I95.1 - Orthostatic hypotension

Clinical Definition

Bone marrow transplant rejection occurs when transplanted donor stem cells are attacked and destroyed by the recipient's immune system. This prevents successful engraftment and restoration of normal blood cell production.

Documentation Requirements

• Specify type of transplant rejection (host-versus-graft or graft-versus-host)

• Document timing:

  • Days since transplant

  • When rejection symptoms first appeared

• Note objective evidence:

  • Decreasing blood counts

  • Chimerism studies results

  • Bone marrow biopsy findings

• Record specific symptoms:

  • Fever

  • Skin rash

  • GI symptoms

• Include any contributing factors:

  • HLA matching status

  • Immunosuppression compliance

  • Infections

Common Synonyms

• Graft failure

• Transplant failure

• BMT rejection

• Marrow rejection

• Failed engraftment

Coding Conflicts

Excludes1:

• Mechanical complications of bone marrow transplant

• Infections related to transplant without rejection

• Complications of immunosuppressive medications

Scribing.io Automation

Our AI scribe automatically identifies:

• Language indicating graft rejection vs. failure

• Temporal relationships to transplant date

• Laboratory values suggesting rejection

• Associated symptoms

• Treatment modifications made in response
  The system flags documentation gaps like missing timing or objective evidence for coder review.